Chemical investigations on the spiny sea-star Marthasterias glacialis collected in Portugal as a source of bioactive molecules

  • D.M. Pereira REQUIMTE/Laboratório de Farmacognosia, Departamento de Química; Laboratório de Bioquímica, Departamento de Ciências Biológicas; Faculdade de Farmácia, Universidade do Porto
  • F. Ferreres Research Group on Quality, Safety and Bioactivity of Plant Foods, Department of Food Science and Technology, CEBAS (CSIC), P.O. Box 164, 30100 Campus University Espinardo, Murcia, Spain
  • P. Valentão REQUIMTE/Laboratório de Farmacognosia, Departamento de Química, Faculdade de Farmácia, Universidade do Porto, Portugal
  • Natércia Teixeira Laboratório de Bioquímica, Departamento de Ciências Biológicas, Faculdade de Farmácia; IBMC – Instituto de Biologia Molecular e Celular, Universidade do Porto, Portugal
  • Andrade P.B. REQUIMTE/Laboratório de Farmacognosia, Departamento de Química, Faculdade de Farmácia, Universidade do Porto, Portugal
Keywords: bioactive molecules, Marthasterias glacialis, portuguese coast

Abstract

Marine organisms are increasingly regarded as a promising source of bioactive molecules for human pharmacotherapy, being used in conditions such as cancer, inflammation, infection and pain.

Marthasterias glacialis, also known as the spiny sea-star, is an echinoderm common in the Portuguese coast, however little information is available regarding its chemical constituents.

In this work, the chemistry of this organism is reviewed taking into account the latest reports on several classes of natural products, namely carotenoids, sterols, fatty acids and amino acids.

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